Clinical trials in dementia and Alzheimer's
Clinical trials currently recruiting in Israel
The table below summarizes Relevant clinical trials For the disease Alzheimer's and dementia In progress In Israel, and open Now For Israeli participation.
From time to time, we will update here about additional clinical studies being conducted in Israel, and you are welcome to return to it.
The list includes experiments Medicines Innovation alongside interventions Non-pharmacological (such as cognitive training, nutrition, brain stimulation, etc.).
In the table you will find details about the name of the experiment, the description of the study, who can participate in it, and where the experiment is being conducted.
For some of the clinical trials, we also added Links to registration pages On behalf of the research bodies.
EMDA Association Accepts for registration pages Sponsorships, Used to subsidize, improve, and expand the services and solutions that EMDA provides to the public.
It is important to note that the information about the clinical trials on this page and on the registration pages is published as is, on behalf of the research bodies and the EMDA Association. is not responsible for its accuracy.
Applying and participating in these studies is At your discretion, and at your sole responsibility..
| Name of the experiment | Study Description | Target Audience | Location and link |
|---|---|---|---|
|
AG-05-17 |
Studying the genetics of Alzheimer's disease among non-Ashkenazi Jews |
Jews of non-Ashkenazi origin, aged 65 and over, with memory disorders, MCI or Alzheimer's, and who are not suffering from another type of dementia, Parkinson's or chronic kidney disease. |
In these hospitals: |
|
tDCS4MCR |
Direct Current Brain Stimulation for Motor-Cognitive Risk (MCR) Syndrome |
65–90 years old with memory complaints and slowed gait, without a diagnosis of dementia |
Tel Aviv Medical Center (Ichilov) |
|
Identifying biomarkers for Alzheimer's |
Observational study to detect/validate biomarkers for Alzheimer's disease in patients, to improve diagnosis and understanding of the disease |
Diagnosed with Alzheimer's (eligibility is determined in a screening conversation with the research team) |
Laniado Hospital, Netanya |
|
SCI-110 |
Combining cannabinoids to reduce agitation and aggression in Alzheimer's |
Alzheimer's patients with BPSD (suffering from restlessness) |
The Israeli Alzheimer's Medical Center (IDC) |
|
KarXT for Alzheimer's psychosis |
Experimental drug (xanomeline + trospium) for moderate-severe psychosis (Phase III) |
Alzheimer's patients with psychosis |
International study, including 5 hospitals in Israel: Rambam, Sheba, Hadassah Ein Kerem, Beilinson, Barzilai |
|
Chervonin |
Blood biomarkers of active brain damage in response to cervonin treatment, testing for inhibition of the brain disease process that causes dementia |
People aged 65 and over with Alzheimer's-type MCI |
Hadassah Ein Kerem Medical Center |
|
Promoting a healthy lifestyle and maintaining brain and cognitive health |
Promoting culturally appropriate brain health: An evaluation across ethnic groups |
Ecclesiastical and Jewish subjects aged 55 to 80 years, men and women, without known cognitive decline and without significant cognitive complaints |
Rambam Hospital, Haifa |
|
TabCAT-BHA (Computerized Cognitive Test) |
A brief cognitive assessment for the Arab population in the State of Israel |
Arabic speakers, an experimental group – people with mild cognitive impairment (MCI) and early dementia, and a control group of people without cognitive impairment |
Rambam Hospital, Haifa |
|
Dementia and blood and dietary hyperglycemia in type 2 diabetes |
Blood and dietary hyperglycemic products in type 2 diabetes and their associations with cognitive decline, Alzheimer's disease pathology, and cerebrovascular disease |
Ages 65 and older from the Greater Tel Aviv area: In the experimental group – 2000 Maccabi members registered in the diabetes registry; In the control group – 2000 Maccabi members who are not registered in the diabetes registry |
Sheba Medical Center, Tel Hashomer |
Non-clinical trials currently recruiting in Israel
The table below summarizes Experiments No Clinically relevant For the disease Alzheimer's and dementia and those being carried out In Israel and open Now For Israeli participation.
For some of the trials, we have also added links to registration pages from the research organizations, or contact information for registration. EMDA receives confidential information for such referrals and registration pages, which is used to subsidize, improve, and expand the services and solutions that EMDA provides to the public.
It is important to note that the information about the trials on this page and on the registration pages is published as is, on behalf of the research bodies and the EMDA Association. is not responsible for its accuracy.
Applying and participating in these studies is At your discretion, and at your sole responsibility..
| Name of the experiment | Study Description | Target Audience | . |
|---|---|---|---|
|
Coping with Alzheimer's in families in Israel |
In-depth interviews about a man with Alzheimer's and two of his family members' coping with the disease |
A person aged 75 or over with Alzheimer's or MCI, who is able to speak and identifies their immediate family members. In addition – his spouse and one of his children, who care for him. |
The interviews will take place throughout the country, at a location of the participants' choosing. The research itself was conducted at the University of Haifa. |
|
Close communication and identification of emotional states in a person with dementia. |
In-depth interviews with family members caring for a person with dementia on emotional aspects, how to recognize the emotions of the person with dementia and what to do. |
Family members caring for a person with dementia. |
Face to face or via Zoom. For details and registration: |
Clinical trials that are no longer recruiting participants
Below is information about additional experiments. Not possible Join them. These are experiments. are active already They are not recruiting. Participants, alongside clinical trials that have already are overYou may be interested in finding out what conclusions were drawn from these experiments.
| Name of the experiment | Study Description | Target Audience | . |
|---|---|---|---|
|
EVOKE / EVOKE+ |
Oral semaglutide to slow deterioration in early Alzheimer's (active study) |
MCI/mild dementia with evidence of amyloid |
Sheba, Ichilov, Beilinson, Rambam |
|
Donanemab – TRAILBLAZER |
Anti-amyloid antibody; slowing deterioration in early AD (trial completed) |
MCI/mild dementia with amyloid |
A multinational study (including Israel) has been completed. |
Experiments abroad that may be relevant to Israelis
– Online interventions (Memory training, remote exercise): Sometimes open globally; requires individual review if accepting participants from Israel.
– Supplement/nutritional studies : Some ship product and perform online tracking; regulatory approval is required for shipping to Israel.
– Complex drug trials : Most require physical travel to a research center abroad (blood tests/imaging/infusions)
Support and Advice Center *8889
A listening ear and advice for family members and patients. You can call from any phone.